MicroRNAs相关的胃癌研究进展
王科明;沈群
【期刊名称】《现代肿瘤医学》 【年(卷),期】2011(019)003
【摘要】MicroRNAs ( miRNAs ) is a class of single strand, small non - coding RNAs of about 22 nucleotides.MiRNAs has the functions to regulate gene expression post - transcriptionally and control a wide array of biological processes such as proliferation, differentiation and apoptosis.Recent studies have shown that it involved in regulatory molecules in gastric cancer.Here we present an overview of our current understanding
of
miRNAs
and
their
roles
in
gastric
cancer.%MicroRNAs(miRNAs)是一类广泛存在于真核细胞中长22-25nt 的单链、非蛋白编码RNA,具有转录后基因调控的功能,调节细胞增殖、凋亡以及分化等多种生物学过程.近年来研究发现,miRNAs 与胃癌的发生、发展关系密切.本文就与胃癌相关的miRNAs 及其在肿瘤发生、发展中的研究进展作一综述. 【总页数】3页(612-614) 【关键词】microRNAs;胃癌;进展 【作者】王科明;沈群
【作者单位】南京中医药大学,江苏,南京,210029;南京中医药大学第一附属医院,江苏,南京,210029 【正文语种】中文 【中图分类】R735.2
MicroRNAs相关的胃癌研究进展
