Anti-Inflammatory Mechanism of Total Glycosides of Acanthopanax Giraldii

Anti-Inflammatory Mechanism of Total Glycosides

of Acanthopanax Giraldii

袁芳;陈杰;许国敏;郑加嘉;龙启才

【期刊名称】《中国结合医学杂志：英文版》 【年(卷),期】2009(000)003

【摘要】Objective:To study the anti-inflammatory mechanisms of total glycosides of Acanthopanax Giraldii (TGA).Methods:The changes of prostaglandin E_2(PGE_2),tumor necrosis factor(TNF-α),nitric oxide(NO), and expressions of COX-1 mRNA and COX-2 mRNA in BALB/c mouse macrophages were observed by the radioimmunoassay,ELISA and nitric acid reduction and RT-PCR in the presence or absence of TGA.Results: (1) TGA could significantly decrease the production of PGE_2 and NO in mouse peritoneal macrophages.The inhibitory... 【总页数】6页(P.) 【关键词】

【作者】袁芳;陈杰;许国敏;郑加嘉;龙启才 【

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Institute;of;Clinical;Pharmacology;School;of;Pharmaceutical;Sciences;Sun;Yat-sen;University;Department;of;Pharmacy;the;First;Affiliated;Hospital;Shenzhen;Buji;People;s;Hospital 【正文语种】英文