福多司坦联合布地奈德治疗慢性阻塞性肺疾病急性加重期
的临床研究
杨青茹;李若然
【期刊名称】《现代药物与临床》 【年(卷),期】2017(032)012
【摘要】Objective To investigate the clinical effect of fudosteine combined with budesonide in treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Patients (106 cases) with AECOPD in Xuzhou Central Hospital from August 2016 to August 2017 were randomly divided into control (53 cases) and treatment (53 cases) groups. Patients in the control group were atomization inhalation administered with Budesonide Suspension for inhalation, 1 mg/time, three times daily. Patients in the treatment group were po administered with Fudosteine Tablets on the basis of the control group, 0.4 g/time, three times daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, arterial blood gas indexes, pulmonary function, serological indexes and oxidative stress levels in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 81.13% and 94.34%, respectively, and there were differences between two groups (P < 0.05). After treatment, the pO2 and SaO2 in two groups was significantly increased, but the pCO2
福多司坦联合布地奈德治疗慢性阻塞性肺疾病急性加重期的临床研究
