急性脑梗死320排 CT 脑灌注成像分析
阮志兵;段庆红
【期刊名称】《实用放射学杂志》 【年(卷),期】2014(000)008
【摘要】Objective To explore the clinical value of whole-brain CT perfusion imaging with 320-detector row CT in early acute cerebral infarction.Methods The CTP parameters(CBF,CBV,MTT,TTP)and its pseudo color map of 25 patients with early acute cerebral infarction were retrospectively analysed and compared between infarction area,ischemic penumbra (IP)and the con-tralateral normal region.Results The abnormal perfusion area were found on CTP in 25 patients with early acute cerebral infarction. CTP showed cerebral blood flow (CBF)and cerebral blood volume (CBV)decreased significantly,mean transit time (MTT)short-ened significantly,time to peak (TTP)was significantly longer than those of the contralateral normal region in 7 cases of acute cere-bral infarct core.18 cases of IP lesions showed CBF decreased slightly,CBV increased slightly or maintain normal,MTT and TTP extension compared with contralateral.CBF,CBV,MTT,TTP values had significantly differences between infarct region and the contralateral corresponding normal region,between the infarct core area and IP of acute cerebral infarction (P <0.01).CBF,MTT, TTP values had statistically significant(P <0.05),and CBV values was not statistically significant
(P >0.05)between IP region and the contralateral corresponding normal region,but showed a downward trend in blood flow.Parameter color maps of CTP could di-rectly,clearly and sensitively show abnormal changes region about cerebral blood flow.In particular,MTT and TTP maps shows ab-normal region clearer and sensitively.Follow-up 18 cases of IP,active lesions deduced in 6 cases,the lesions disappeared in 5 pa-tients (CT/ MRI showed no abnormal,and the clinical symptoms disappeared)after thrombolytic therapy,7 cases of MRI and CT scans confirmed infarction stove.Conclusion Whole-brain CTP with 320-detector row CT can early show the acute cerebral infarc-tion and its ischemic penumbra,it has significant important clinical value for early acute cerebral infarction.%目的：探讨320排 CT 全脑灌注成像(CTP)在早期急性脑梗死中的临床应用价值。方法回顾性分析25例早期急性脑梗死的320排 CT 脑灌注成像资料,对比分析 CTP 灌注参数(CBF、CBV、MTT、TTP)和其对应灌注伪彩图在脑梗死区、缺血半暗带区(IP)及对应健侧区的变化。结果25例患者全脑 CTP 均发现灌注异常区,7例核心梗死区表现为 CBF 与 CBV 均较健侧明显下降,MTT 较健侧缩短,TTP 均较健侧明显延长；18例 IP 病灶 CBF 较健侧稍降低,CBV 较健侧稍增加或维持正常,MTT 及 TTP 均较健侧延长。脑梗死区与健侧对应区域比较,CBF、CBV、MTT、TTP 值均有显著性差异(P <0.01)；急性脑梗死 IP 区与梗死核心区比较,CBF、CBV、MTT 及 TTP 值差异均有明显统计学意义(P <0.01)；IP 区与健侧对应区比较,CBF、MTT、TTP 值差异均具有统计学意义(P <0.05),CBV 值差异无统计学意义(P >0.05),但显示血流呈下降的
趋势。CTP 各参数相对应的伪彩图,可直接、形象地显示脑梗死区域血流的异常变化,尤其 MTT 图与 TTP 图对显示异常更清晰、敏感。结论320排 CT 全脑灌注成像对急性脑梗死的早期发现和判断是否存在缺血半暗带具有重要的价值。 【总页数】4页(1259-1262)
【关键词】灌注成像;计算机体层成像;急性脑梗死 【作者】阮志兵;段庆红
【作者单位】贵阳医学院附属医院影像科，贵州 贵阳 550004;贵阳医学院附属医院影像科，贵州 贵阳 550004 【正文语种】中文
【中图分类】R814.42;R743.33 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_journal-practical-radiology_thesis/0201239636203.html 【相关文献】
1.320排CT全脑灌注成像不同输入动脉对急性脑梗死灌注参数的影响 [J], 陈兆乾; 黄求理; 潘宇宁; 叶贤旺; 张杰
2.320排动态容积CT全脑灌注成像技术在脑梗死中的临床应用 [J], 向永华; 王波; 金科; 裴贻刚; 杨伟; 汪春红
3.64层螺旋CT脑灌注成像在急性脑梗死诊断中的应用 [J], 甘中亮; 吴耀贤; 余海波
4.64排螺旋CT脑灌注成像联合头颈部血管成像在急性脑梗死中的应用 [J], 朱建国; 杨亚芳; 刘斐; 唐继来; 沈世田; 顾生荣; 万谦; 史永平; 朱成红
急性脑梗死320排 CT 脑灌注成像分析
