[3+3] Formal Cycloadditions of Nitrones from Isatins and Azaoxyallyl Cations for Construct

[3+3] Formal Cycloadditions of Nitrones from Isatins and Azaoxyallyl Cations for Construction of

Spirooxindoles

Weijia Lin;Gu Zhan;Minglin Shi;Wei Du;Yingchun Chen

【期刊名称】《中国化学（英文版）》 【年(卷),期】2017(035)006

【摘要】A [3 +3] formal cycloaddition reaction between in situ formed azaoxyallyl

cations

and a good

nitrones

from of

isatins

has

been

developed,furnishing one]oxindoles

in

spectrum to

spiro[1,2,4-oxadiazinan-5-yields

with

excellent

excellent

diastereoselectivity.This method provides direct and efficient access to potentially bioactive spirooxindoles incorporating a six-membered heterocyclic scaffold. 【总页数】4页(857-860) 【关键词】

【作者】Weijia Lin;Gu Zhan;Minglin Shi;Wei Du;Yingchun Chen

【作者单位】Department of Medicinal Chemistry, West China School of Pharmacy,

Sichuan

University,Chengdu,

Sichuan

610041,

China;Department of Medicinal Chemistry, West China School of Pharmacy,

Sichuan

University,Chengdu,

Sichuan

610041,

China;Department of Medicinal Chemistry, West China School of Pharmacy,

Sichuan

University,Chengdu,

Sichuan

610041,