急性ST段抬高心肌梗死患者再灌注损伤性心电图改变与炎
症及氧化应激的关系
蒋娜;匡希斌
【期刊名称】《中南医学科学杂志》 【年(卷),期】2014(000)002
【摘要】Objective To explore the characteristics of reperfusion injury electrocardiogram changes and their asso-ciation with inflammation and oxidative stress in patients with acute ST segment elevation myocardial infarction. Methods Eighty acute ST segment elevation myocardial infarction patients who had been unobstructed by percutaneous coronary inter-vention (PCI) were divided into reperfusion injury electrocardiogram change group (n=48) and without reperfusion injury electrocardiogram change group (n=32) according to the results of electrocardio monitoring. The concentrations of tumor necrosis factor-α (TNF-α),interleukin-1β (IL-1β) and interleukin-6 (IL-6) were detected by ELISA. Serum contents of malondialdehyde (MDA) and activities of superoxide dismutase (SOD),glutathione-peroxidase (GSH-Px) and catalase ( CAT) were examined. Results The incidence of reperfusion injury arrhythmia was 60. 00%,especially accelerated id-ioventricular rhythm,and that of reperfusion injury ST segment elevation was 36. 25% in patients with acute ST segment ele-vation myocardial infarction.
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急性ST段抬高心肌梗死患者再灌注损伤性心电图改变与炎症及氧化应
