The thickness and volume of the choroid,outer retinal layers and retinal pigment epitheliu

The thickness and volume of the choroid,outer retinal layers and retinal pigment epithelium layer changes in patients with diabetic retinopathy

Xiang-Ning Wang[1];Shu-Ting Li[1];Wei Li[1];Yan-Jun Hua[1];Qiang Wu[1,2];;

【期刊名称】《国际眼科杂志：英文版》 【年(卷),期】2018(000)012

【摘要】AIM:To evaluate the thickness and volume changes of the choroidal,outer retinal layers (ORL)and retinal pigment epithelium (RPE)in patients with diabetic retinopathy (DR) using optical coherence tomography (OCT)and correlate them with visual acuity. METHODS:We carried out a retrospective observational case series.Consecutive DR patients were recruited for color fundus photography and OCT assessment.The RPE,ORL and choroidal thickness were measured.The correlation with the best-corrected visual acuity (BCVA) was also investigated. RESULTS:The study included 128eyes,comprising 45 eyes of 25diabetic macular edema (DME)patients,34 eyes of 20DR without DME (non-DME)patients,and 49 eyes of 25age-matched normal individuals.The choroidal thickness in DR patients were decreased statistically significantly compared with the control group (P<0.05). The mean macular ORL thickness in DME (73.02±15.34μm) and non-DME groups

(76.35±7.32μm)were with

the

control

decreased group

statistically

significantly

compared (80.20±5.85μm;P=0.006,P=-