Time course of expression of intermediate filament protein vimentin, nestin and desmin in

Time course of expression of intermediate filament protein vimentin, nestin and desmin in rat renal

glomerular injury

ZOU

Jun;CHANG

Tian-hui;CHANG

He;Eishin

Yoshida;Masaaki

Yaoita;Yutaka

Nameta;Tadashi Yamamoto;JIN Xin

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2007(120)013

【摘要】@@ Podocytes in renal glomerulus express unusual intermediate filament proteins (IFs) for visceral epithelial cells. IFs cytoskeleton is mainly composed of vimentin, nestin and desmin. Tissue injury is often accompanied by changes in gene expression of IFs.1 Enhanced desmin staining in podocytes are observed in a variety of rat experimental models of podocyte injury including puromycin aminonucleoside (PAN)nephrosis.2-4 It has not been elucidated whether expression of vimentin and nestin is up-regulated in podocyte injury. To further gain insight into expression of IFs in podocytes, we investigated the time course of vimentin, nestin and desmin in PAN nephrosis.

【总页数】3页(1203-1205)

【关键词】intermediate filament;vimentin;nestin;desmin;kidney

【作者】ZOU Jun;CHANG Tian-hui;CHANG He;Eishin Yaoita;Yutaka Yoshida;Masaaki Nameta;Tadashi Yamamoto;JIN Xin