A comparative study of the antioxidant,antimicrobial,cytotoxic and thrombolytic potential

A comparative study of the

antioxidant,antimicrobial,cytotoxic and thrombolytic potential of the fruits and leaves of

Spondias dulcis

shawkat Md.Aminul Islam; kh Tanvir Ahmed; Mohammad Kawsar Manik; Md.Arif Wahid; chowdhury shafayat ibne Kamal

【期刊名称】《《亚太热带生物医学杂志：英文版》》 【年(卷),期】2013(000)009

【摘要】Objective:To investigate the antioxidant,antimicrobial,cytotoxic and thrombolytic property of the fruits and leaves of Spondias dulcis（S.dulcis）.Methods:Methanolic extracts of fruits and leaves of S.dulcis were partitioned with chloroform and dichloromethane.The antioxidant potential of the crude extract and partitioned fractions were evaluated in terms of total phenolic content,total flavonoid content,DPPH radical scavenging potential,reducing potential and total antioxidant capacity by specific standard procedures.The antimicrobial activity was evaluated using disc diffusion method.The cytotoxicity was evaluated by using brine shrimp lethality bioassay and compared with vincristine sulfate.The

thrombolytic

activity

was

compared

with

streptokinase.Results:The methanolic fruit extract exhibited the highest phenolic content,flavonoid content and antioxidant capacity,among the other extracts,with the highest DPPH radical scavenging activity at a

concentration of 10μg/mL(IC 【总页数】10页(P.682-691)

【关键词】Spondias dulcis Antioxidant activity Antimicrobial activity Cytotoxic activity Thrombolytic activity DPPH IC; LC;50

【作者】shawkat Md.Aminul Islam; kh Tanvir Ahmed; Mohammad Kawsar Manik; Md.Arif Wahid; chowdhury shafayat ibne Kamal 【作者单位】Department of Pharmacy East West University 【正文语种】中文 【中图分类】R151 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_asian-pacific-journal-tropical-biomedicine_thesis/0201273772681.html 【相关文献】

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