Interleukin-10 genotype protects end stage renal disease patients from microinflammation a

Interleukin-10 genotype protects end stage renal disease patients from microinflammation and

arteriosclerosis

WU Hong-chi;LING Hong;NA Shi-ping;XIE Ru-juan

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2005(118)018

【摘要】@@ End stage renal disease (ESRD) and cardiovascular disease are induced by arteriosclerosis (AS). The latest investigation shows that AS is a special inflammatory state. The constant inflammation,which has been defined as a micro inflammatory state is related to the decline of renal function and blood purification, but not the result of infections caused by external pathogenic microorganisms or internal opportunistic pathogenic microorganisms. We investigated the mechanism of interleukin-10 (IL-10) gene-1082 A/G protection effect to keep ESRD patients away from micro inflammation and AS. 【总页数】3页(1549-1551)

【关键词】end stage renal disease;interleukin-10;micro-inflammatory state;arteriosclerosis

【作者】WU Hong-chi;LING Hong;NA Shi-ping;XIE Ru-juan

【作者单位】Department of Nephrology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, China;Department of Immunity, Harbin Medical University, Harbin 150001, China;Department of