Anti-inflammatory activity of the leaf extacts
ofGendarussa vulgaris Nees
TK Mohamed Saleem;AK Azeem;C Dilip;C Sankar;NV Prasanth;R Duraisami
【期刊名称】《亚太热带生物医学杂志（英文版）》 【年(卷),期】2011(000)002
【摘要】Objective:To evaluate the anti-inflammatory property of the leaf exacts ofGendarussa vulgaris (G. vulgaris) Nees.Methods:G. vulgaris Nees of the family Apocynaceaeis a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers, sores, inflammation, dyspepsia, healing of wounds,etc. The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro andin vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation (HRBC) method andin vivo method was estimated on the carrageenan induced paw oedima.Results: Both the methods showed significant anti-inflammatory property of the different extracts tested. Conclusions: The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium. 【总页数】3页(147-149) 【关键词】
Anti-inflammatory activity of the leaf extacts ofGendarussa vulgaris Nees
