老年心力衰竭患者心功能与血浆B型钠尿肽和尿酸的相关
性研究
舒燕;姜荣建;孔洪;李其勇
【期刊名称】《中华老年心脑血管病杂志》 【年(卷),期】2014(000)010
【摘要】Objective To study the correlation of heart function with plasma BNP and serum uric acid (UA) levels in elderly heart failure patients .Methods One hundred and thirty-two elderly patients with chronic heart failure (CHF)served as a CHF group in this study .They were divided into class Ⅰ group (n=26) ,class Ⅱ group (n=38) ,class Ⅲ group (n=40) ,and class Ⅳ group (n=28) according to the NYHA Classification .Fifty healthy subjects undergoing physical exami-nation served as a control group .Their plasma BNP and erum UA levels were measured and com-pared .Results The plasma BNP and erum UA levels were significantly higher in CHF group than in control group (784 .19 ± 206 .00 ng/L vs 41 .25 ± 15 .34 ng/L ,405 .24 ± 90 .16 μmol/L vs 286 .43 ± 78 .68 μmol/L ,P<0 .01) and were significantly different in class Ⅰ - Ⅳ groups (P<0.05 ,P<0 .01) .The plasma BNP level was positively correlated with the NYHA Classification , serum UA level and LVEDD ,and negatively correlated with the LVEF in CHF patients (r=0 .76 , 0 .33 ,0 .22 ,P<0 .05 ;r= -0 .34 ,P<0 .0 5) .The serum UA level was positively correlated with the NYHA Classification and LVEDD ,and