Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculatu

Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography

Based on Optical Microangiography

ZHAO Qi;WANG Zi Yang;CHEN Wei;LI Yi Feng;CUI Rui;SHEN Lin;WEI Wen Bin;YANG Wen Li;WANG Xiao Na;Ruikang K Wang;YOU Qi Sheng;CHU Zhong Di;XIN Chen;ZHANG Meng Yu;LI Dong Jun

【期刊名称】《生物医学与环境科学（英文版）》 【年(卷),期】2024(031)006

【摘要】Objective The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography (OCTA) based on optical microangiography (OMAG) measurements of macular vessels in normal eyes. Methods In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA (Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network: vessel area density (VAD), vessel skeleton density (VSD), vessel diameter index (VDI), vessel perimeter index (VPI), vessel complexity index (VCI), flux, and foveal avascular zone (FAZ). Coefficient of variation (CV) and intraclass correlation coefficient (ICC) were calculated for