左氧氟沙星与甲硝唑联合应用预防急性阑尾炎围术期感染
的效果观察
游琳
【期刊名称】《医药前沿》 【年(卷),期】2013(000)005
【摘要】 目的:探讨左氧氟沙星与甲硝唑联合应用预防急性阑尾炎围术期感染的效果。方法:将我院2007年~2009年间收治的84例急性阑尾炎手术患者随机分为观察组和对照组,每组各42例,对照组患者在围手术期常规治疗基础上给予甲硝唑治疗,观察组患者在常规治疗基础上给予左氧氟沙星联合甲硝唑治疗,观察两组患者的感染发生率、伤口愈合时间和住院时间。结果:观察组患者的感染发生率为4.8%,显著低于对照组患者的19.0%,组间差异有统计学意义(P<0.05),同时观察组患者的伤口愈合时间和住院时间明显少于对照组患者,差异有统计学意义(P<0.05)。结论:将左氧氟沙星联合甲硝唑应用于预防急性阑尾炎患者围手术期感染效果好,能够降低切口感染率,促进患者术后恢复。%Objective To explore the effect of combined application of leofloxacin and metronidazole in preventing perioperative period infection of acute appendicitis. Methods 84 patients with acute appendicitis in our hospital from 2007 to 2009were randomly divided into observation group and control group, 42 cases in each group, on the basis of conventional treatment patients in the control group were treated by metronidazole in operation perioperative period, patients in the observation group were treated by levofloxacin combined with