伴肾小球IgA沉积的抗中性粒细胞胞浆抗体相关性小血管
炎的分析
华胄;马雁鸿;陈亮亮;俞斌峰;徐莹;王慧萍;陈江华;韩飞
【期刊名称】《中华肾脏病杂志》 【年(卷),期】2018(034)003
【摘要】Objective To investigate the clinical manifestations,renal pathology and prognosis of antineutrophil cytoplasmic antibody-associated small-vessel vasculitis (AAV) accompanied with renal glomerular IgA deposition.Methods A retrospective analysis was performed at the First Affiliated Hospital of Zhejiang University College of Medicine.Patients diagnosed with AAV associated renal injury by renal biopsy from February 2004 to February 2017 were enrolled.Patients with antiglomerular basement membrane antibody-mediated nephritis,systemic lupus erythematosus nephritis,Henoch Schonlein purpura nephritis,hepatitis B virus associated nephritis and other known etiology were excluded.According to immunofluorescence examination,the patients were divided into IgA deposition group and pauci-immune complex deposition group.The differences in clinical manifestation,pathological features and prognosis were compared between groups.Results A total of 150 AAV cases were included,among which 25 cases were with IgA deposition and 125 cases with pauci-immune complex deposition.The level of serum albumin in IgA
伴肾小球IgA沉积的抗中性粒细胞胞浆抗体相关性小血管炎的分析
