Prognosis of R1-resection at the bronchial stump in patients with non-small cell lung cancer

Prognosis of R1-resection at the bronchial stump

in patients with non-small cell lung cancer

Lyu Jima;Hao Xuezhi;Hui Zhouguang;Liang Jun;Zhou Zongmei;Feng Qinfu;Xiao Zefen

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2014(127)016

【摘要】Background The prognosis of R1-resection at the bronchial stump in patients with non-small cell lung cancer (NSCLC) remains unclear.This study intends to identify the prognostic factors and to optimize

treatments

for

these

patients

under

update

conditions.Methods The data of 124 NSCLC patients who underwent R1-resection at the bronchial stump was reviewed.There were 41 patients in the surgery group (S),21 in the postoperative radiotherapy (PORT) group (S+R),30 in the postoperative chemotherapy (POCT) group (S+C),and 32 in the PORT plus POCT group (S+R+C).The constitute proportion in different groups was tested using the X2 method,univariate analysis was performed using the Kaplan-Meier and log-rank method,and multivariate analysis was done using the Cox hazard regression with entry factors including age,sex,pathological type and stage,classification of the residual disease,and treatment procedure.The process was performed stepwise backward with a maximum iteration of 20 and an entry possibility of 0.05 as well as an excluded possibility of 0.10 at each step.Results In univariate