A case of recurrent neuroleptic malignant
syndrome
Zexiang OUYANG*, Li CHU 【期刊名称】上海精神医学 【年(卷),期】2013(000)004 【总页数】3 ?Case report?
1. Case history
A 46-year-old female with a four-year history of disorganized speech, lack of impulse control and insomnia was admitted for her first hospitalization in May 2006 at the Sixth People’s Hospital of Anqing because her symptoms had exacerbated over the prior two months. After being diagnosed with schizophrenia on admission, she was treated with intramuscular haloperidol 10 mg bid and oral aripiprazole 10 mg bid. After one week of treatment,her temperature rose to 39.8 oC and her pulse increased to 110/min. She experienced urinary retention, became disoriented and then lost consciousness. Her muscles became rigid and she showed no spontaneous movement.Blood tests showed a leukocyte level of 14.8×109/L, with a neutrophil percentage of 63.0%. Blood biochemistry found that creatine kinase (CPK) was 1794 u/L, alanine transaminase (ALT) was 139 u/L, and glutamic oxaloacetic transaminase (SGOT) was 128 u/L. The patient was then given a