灼口综合征三叉神经诱发电位的初步研究
王雨生;高山;王正坤;刘士有;李长福
【期刊名称】《现代口腔医学杂志》 【年(卷),期】2001(015)003
【摘要】目的通过电生理学手段检测BMS患者痛阈值,记录三叉神经诱发电位变化,以期推测神经传导过程中的病理状态,进一步探讨其发病机制。方法以神经肌电图仪刺激患者舌背,共记录38个样本(灼痛者22,麻胀者10,对照组6)感知最小刺激量为痛阈,3倍阈值刺激舌神经,记录诱发电位中N3、N4的潜伏期及高峰电位的出现时间。结果灼痛组痛阈值降低,N3、N4潜伏期缩短,高峰电位出现明显提前,与其他两组比较具有显著性差异(P<0.01),麻胀组则呈相反趋势,与对照组比较无显著差异(P>0.05)。结论 BMS灼痛者神经兴奋性提高,对外界刺激易感;麻胀组则可能存在神经部分或完全传导阻滞。说明BMS灼痛报告真实可信,同时反映出神经传导过程中病理状态存在的可能性,显示出BMS可能存在的发病机制。%Objective The measurement of pain threshold (PT) and the assessment of trigeminal somatosensory evoked potentials (TSEPs) were performed.In order to estimate the pathological conditions of nerve afferent and efferent pathways in patients with burning mouth syndrome (BMS),and explore the probable pathophysiological mechanisms in BMS.Methods The lingual dorsum of thirty eight samples in nineteen subjects (inclusion of 22 BMS with pain,10 of BMS with Dumb and 6 of control group) were stimulated by electroneuromyography.PT was measured as the minor