ICU中老年患者中心静脉导管相关感染的临床及病原学研
究
梁科;黄宗校;杨杰文
【期刊名称】《中国医学前沿杂志（电子版）》 【年(卷),期】2014(000)006
【摘要】Objective To investigate the correlation of blood ICU in elderly patients with central venous catheter infection (CRBSI) study on the etiology, analysis of drug resistance of the pathogenic bacteria, and evaluate the risk factors of infection and prevention measures. Method From June 2011 to June 2013, the clinical data of 300 patients in our hospital ICU tube central vein, the risk factors for the development of CRBSI, the pathogenic bacteria culture and drug resistance were analyzed retrospectively. Result 300 cases of ICU central venous catheters were CRBSI 38 cases (12.7%), wherein the subclavian vein catheterization in 120 cases, 9 cases of CRBSI (7.5%);the internal jugular vein catheterization in 105 cases, 12 cases of CRBSI (11.4%); femoral vein catheterization in 75 cases, 17 cases of CRBSI who (22.7%); femoral vein catheter infection rate was the highest, and subclavian and carotid stent comparison, the difference was statistically signiifcant (P<0.05). A total of 38 cases of pathogenic bacteria in 46 cases, in which G+bacteria accounted for 29 cases (0.63%), G-bacteria accounted for 13 cases (28.3%), 4 cases of fungus (8.7%);CRBSI pathogen in epidermal
staphylococcal and Bauman Acinetobacter, where G+drug resistance of bacteria to vancomycin 0, while the G -bacteria were most sensitive to imipenem. Infection and the indwelling time of indwelling position,>15 days, diabetes, age>70 years old, and mechanical ventilation and so on (P<0.05), gender is not associated with infection (P>0.05). Conclusion ICU center in elderly patients with venous catheter related bloodstream infection is easy to occur, clinical staff should strengthen the concept of aseptic operation, reduce the risk as far as possible, early to the prevention and control measures, to reduce the infection rate.%目的：探讨ICU中老年患者中心静脉导管相关血流性感染（CRBSI）的病原学研究，分析其病原菌的耐药情况，同时评估其感染的危险因素及防治措施。方法收集2011年6月至2013年6月在本院ICU行中心静脉置管的300例中老年患者的临床资料，对其发生CRBSI的危险因素、病原菌培养及耐药情况进行回顾性分析。结果在ICU 300例留置中心静脉导管的中老年患者中发生CRBSI 38例（12.7%），其中锁骨下静脉穿刺置管120例，发生CRBSI 9例（7.5%）；颈内静脉穿刺置管105例，发生CRBSI 12例（11.4%）；股静脉穿刺置管75例，发生CRBSI 17例（22.7%）；股静脉穿刺置管感染率最高，与锁骨下及颈内静脉穿刺置管比较差异具有显著性（P＜0.05）。38例共培养病原菌46例，其中G＋球菌29例（0.63%），G-杆菌13例（28.3%），真菌4例（8.7%）；CRBSI病原菌中以表皮葡萄糖球菌及鲍曼不动杆菌为主，其中G＋球菌对万古霉素的耐药性为0，而G-杆菌对亚胺培南最敏感。感染与留置部位、静脉导管留置时间＞15天、糖尿病、年龄＞70岁以及行机械通气等因素相关（P＜
0.05），性别与感染无关（P＞0.05）。结论 ICU中老年患者留置中心静脉导管易发生相关血流性感染，临床医务人员应加强无菌操作观念，尽可能降低其危险因素，早期给予防治措施，以降低感染率。 【总页数】3页(158-160)
【关键词】ICU;中心静脉导管;病原学;危险因素 【作者】梁科;黄宗校;杨杰文
【作者单位】东莞广济医院 重症医学科，广东 东莞 523690;东莞广济医院 重症医学科，广东 东莞 523690;东莞广济医院 重症医学科，广东 东莞 523690 【正文语种】中文 【中图分类】 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-journal-frontiers-medical-science-electronic-version_thesis/0201254164685.html 【相关文献】
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2.ICU中心静脉导管相关性感染病原学及临床特征分析 [J], 于爱利
3.ICU老年患者中心静脉导管相关性血流感染的病原学分析 [J], 任志慧; 冯伟 4.老年患者中心静脉导管相关血流感染的因素及病原学分析 [J], 梁蓓; 叶寰; 李晓鹏; 薛天娇
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ICU中老年患者中心静脉导管相关感染的临床及病原学研究
