Comparison and Evaluation of Several Dermatophagoides Pteronyssinus Allergen Extracts for

Comparison and Evaluation of Several

Dermatophagoides Pteronyssinus Allergen Extracts

for Skin Prick Test

Jin-lu Sun;Rui-qi Wang;Jia Yin;Liang-lu Wang;Hong-yu Zhang;Hong Li;Yu-xiang Zhi;Li-ping Wen;Kai Guan;Jian-qing Gu;Hai-juan He;Ying Zhao;Wei Zhang;Guo-qiang Sun

【期刊名称】《中国医学科学杂志（英文版）》 【年(卷),期】2009(024)002

【摘要】To evaluate the significance of several Dermatophagoides pteronyssinus allergen extracts for skin prick test (SPT) in patients allergic to Dermatophagoides pteronyssinus.Methods Two hundred and nineteen patients enrolled in Peking Union Medical College Hospital underwent SPT and serum specific IgE assay to detect the Dermatophagoides pteronyssinus allergen. Three kinds of house dust mite

allergen

extracts

were

used

for

SPT,

including

the

Dermatophagoides pteronyssinus extract prepared by our laboratory (group A), standardized Dermatophagoides pteronyssinus extract (group B), and mixed extracts of Dermatophagoides pteronyssinus and Dermatophagoidesfarinae (group C). Human serum spe-cific IgE result was regarded

as

the

reference standard

allergy.The

for

diagnosis of

operating

Dermatophagoides pteronyssinus receiver

characteristic (ROC) curve was used to evaluate the diagnostic performance of SPT with the extracts of three groups.Results SPT results