纳米碳混悬液示踪早期舌鳞癌前哨淋巴结的临床研究
钟江龙;范松;陈伟良;李群星;王友元;张大明
【期刊名称】《广东牙病防治》 【年(卷),期】2016(024)002
【摘要】Objective To investigate the efficacy of carbon-nanoparticles suspension in detecting sentinel lymph nodes in cT1-2N0 oral tongue carcinoma and explore the application value of carbon-nanoparticles suspension in sentinel lymph node biopsy. Methods Fifty-eight patients with cT1-2N0 oral tongue carcinoma were enrolled in this prospective trial. Thirty patients received carbon nanoparticle injection around the tumor pre-operatively ( experimental group) , and the remaining 28 were injected with methylene blue dye ( control group) . All patients underwent elective neck dissection and routine pathological examination was performed in all resected specimens. Results The experimental group had a clear surgical field compared with the control group, and there is clear boundary between the staining lymph nodes and surrounding tissue. In the experimental group, the detection rate, sensitivity, accuracy rate, and false negative rate of the carbon-nanoparticles suspension were 96. 7% ( 29/30) , 87. 5% ( 7/8) , 93. 3% ( 28/30) , and 12. 5% ( 1/8) , respec-tively compared with 92. 8% ( 26/28) , 66. 7% ( 4/6) , 85. 7% ( 24/28) , and 33. 3% ( 2/6) , respectively, of the con-trol group. There is no significant difference in both groups
纳米碳混悬液示踪早期舌鳞癌前哨淋巴结的临床研究
