脑胶质瘤术后放疗联合替莫唑胺化疗同步与序贯治疗的对
比
刘培杰;申风乾;张燕;高岭;李宁;徐志巧
【期刊名称】《中国实用神经疾病杂志》 【年(卷),期】2014(000)014
【摘要】Objective To study the clinical effect of the radiotherapy combined
with
synchronizing
chemotherapy
or
se-quential
chemotherapy of temozolomide after glioma surgery.Methods 46 patients after glioma surgery were randomly divided into control group and observation group. Control group adopted radiotherapy combined with temozolomide sequential therapy , observation group adopted radiotherapy combined with temozolomide synchronizing therapy. disease free survival time ,adverse reactions of two groups were compared in the process of treatment.Results free survival time of observation group were signif-icantly longer than that of control group ,the difference was statistically significant (P<0.05). There was no significant differ-ence in incidence of adverse reactions of two groups
,(P>0.05).Conclusion
concurrent
chemoradiotherapy
can
significantly prolong the disease free survival time of patients with cerebral gliomas after surgery ,without increasing side effects ,it’s a bet-ter treatment for glioma surgery.%目的:探讨脑胶质瘤术后放疗联合替莫唑胺化疗同步与序贯疗法治疗的临床效果。方法将我院收治的46例脑胶质