可降解涂层与不可降解涂层雷帕霉素洗脱支架在急性心肌
梗死直接经皮冠状动脉介入治疗中的疗效比较
李强;王乐丰;杨新春;葛永贵;王红石;李惟铭;徐立;倪祝华;夏昆
【期刊名称】《中华心血管病杂志》 【年(卷),期】2010(038)010
【摘要】Objective This prospective random control study was performed to compare the efficacy and safety of primary percutaneous coronary intervention (PCI) with biodegradable polymer ( Excel ) and with durable polymer ( Cypher Select) sirolimus-eluting stents in patients with acute ST-elevation myocardial infarction (STEMI). Methods Consecutive patients with STEMI underwent primary PCI were randomly divided into Cypher group ( n = 113 ) and Excel group ( n = 115 ). The primary endpoints were major adverse cardiac events (MACE, including death, reinfarction and target vessel revascularization) within 12 months.The second endpoints included late luminal loss and restenosis at 9 months. Results Angiographic follow-up data at 9 months were available in 43 (38%) patients in Cypher group and 48 (42%) in Excel group. The rates of in-stent restenosis and in-segment restenosis were 2. 3% vs. 2. 1% (P =0. 937) and 4. 7% vs.6. 3% ( P = 0. 738 ), respectively. The late luminal loss of in-stent and in-segment were (0. 17 + 0. 26 ) mmvs. (0.18 ±0.33)mm (P=0.483) and (0.19 +0.36) mm vs. (0.20 ±0. 42)mm (P=0.419),respectively. There were no significant differences in
可降解涂层与不可降解涂层雷帕霉素洗脱支架在急性心肌梗死直接经
