DNA Damage Caused By Pesticide-contaminated Soil

DNA Damage Caused By Pesticide-contaminated

Soil

K.KRISHNAMURTHI;S. SARAVANA DEVI;T. CHAKRABARTI

【期刊名称】《生物医学与环境科学（英文版）》 【年(卷),期】2006(019)006

【摘要】Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicity of individual compounds present in the soil were assessed using fluorimetric analysis of DNA unwinding assay. Results The contaminated soil sample showed 79% (P＜0.001) of DNA strand break, whereas technical grade of major carbaryl and α-naphthol constituents of the contaminated soil showed 64% (P＜0.01) and 60% (P＜0.02) damage respectively. Conclusion Our results indicate that the toxicity caused by contaminated soil is mainly due to carbaryl and α -napthol, which are the major constituents of the soil sample analyzed by GC-MS. 【总页数】5页(427-431)

【关键词】Carbaryl;Contaminated soil;DNA damage;FADU- Huorimetric analysis of DNA unwinding assay;Genotoxicity;α-Napthol and pesticide 【作者】K.KRISHNAMURTHI;S. SARAVANA DEVI;T. CHAKRABARTI

【作者单位】Environmental Biotechnology Division, National

Environmental Engineering Research Institute (NEERI), Nehru Marg, Nagpur-440020, India;Environmental Biotechnology Division, National Environmental Engineering Research Institute (NEERI), Nehru Marg, Nagpur-440020, India;Environmental Biotechnology Division, National Environmental Engineering Research Institute (NEERI), Nehru Marg, Nagpur-440020, India 【正文语种】中文 【中图分类】X5 【相关文献】

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