接触性热痛诱发电位在亚急性联合变性诊断中的应用
靳梅;谢炳玓
【期刊名称】《中华神经科杂志》 【年(卷),期】2010(043)004
【摘要】Objective To study the characteristics of nociceptive system in subacute combined degeneration (SCD) by contact heat evoked potentials (CHEPs),and evaluate the CHEPs in the electrophysiological diagnosis of SCD.Methods Twenty definite SCD patients and 34 sex-,height-and age-matched healthy controls were included in this study.Thermal stimuli was applied at 51 ℃ intensity level at four sites:C_7,volar surface of the forearm,the skin of leg at 5 cm proximal to the medial malleolus and lumbar part The CHEPs were recorded from Cz.The latency and amplitude of the evoked potentials were recorded.The CV of Aδ fibers of peripheral nerves and N-wave latencies and N-P amplitudes of the central nerves were analyzed.The somatosensory evoked potential (SEP) and sensory conduction dsvelocity (SCV) of the limbs were also evaluated.Results (1) CHEPs were elicited reliably and stably in all controls.(2) The visual analogue scale (VAS) for pain perception was higher in controls (upper limbs:7.6 and lower limbs:6.9) as compared to SCD complication with hypoesthesia (upper limbs:6.4 and lower limbs:5.7,Z = 3.478 and 3.909,both P < 0.01).(3) The conduction velocity of Aδ fibers in upper and lower limbs
接触性热痛诱发电位在亚急性联合变性诊断中的应用
