增殖细胞核抗原在血管瘤组织中的表达及临床意义
程立新;汤少明;罗少军;郝新光
【期刊名称】《中华医学美学美容杂志》 【年(卷),期】2001(007)002
【摘要】Objective In order to study the expression of PCNA in he mangioma and its clinical significance.Methods We devided thirty cases of hemangioma into three groups based on Mulliken classification: eleven cases of proliferating stage(≤one year);nine cases of revoluting stage(≤ five year); ten cases of revolution completed stage(≤ twelve year). Then we investig ated the expression of PCNA in hemangioma samples of these three different stage groups by immunohistochemical streptavidin peroxidase conjugated method.Results The positive cell expression index of PCNA was highest in proliferating stage (62.50±9.49 (37.56±10.57
%),
took
second lowest
place in
in
revoluting
stage
%),was revolution completed
stage(12.20±6.09 %).The differences among these three groups were significant.Conclusion
We concluded from above that PCNA
expressed differently in three different stages of hemangioma, and it can be used as an objective basis for deviding different stages of hemangioma.%目的探讨PCNA在血管瘤中的表达及临床意义。方法根据Mulliken分类法将30例血管瘤标本分为3组:增殖期(≤1岁)11例,退化期(≤5岁)9例,退化完成期(≤12岁)10例,用免疫组化链霉菌抗生物素蛋白-