老年2型糖尿病患者血清炎症因子水平及其与大血管病变
的相关性
洪旭;陈海平;于恒池
【期刊名称】《中国糖尿病杂志》 【年(卷),期】2011(019)008
【摘要】Objective To investigate the serum levels of the inflammatory factors and their relationship with cardiocerebral vascular disease in type 2 diabetes mellitus. Methods The 103 patients with type 2 diabetes mellitus were divided into groups with and without cardiocerebral vascular disease and groups at age of ＜65 and ≥65 years. We detected the levels of serum hsC-RP, fasting blood glucose (FBG), glycosylated hemoglobin ( GHbA1c), cholesterol total (TC), triglyceride (TG), low density lipoprotein-C(LDL-C), serum TNF-α and IL-6. Results (1) The levels of serum hsC-RP, TNF-α and IL-6 were higher in patients of age≥65 years than of age＜65 years (P=0. 003,P=0. 001,P=0. 007).(2)The level of serum hsC-RP was higher in patients with cardiocerebral vascular disease (CCVD) than without CCVD(P=0.015). The level of serum hsC-RP was higher in patients with CCVD and at age of ≥65 years than in patients without CCVD(P=0.040). (3)Serum hsC-RP was positively correlated with age and serum TG(r=0.257,P=0. 000;r=0. 220,P=0. 003). The influencing factor for hsC-RP was age.(4)The incidence rate of CCVD in type 2 diabetes mellitus patients at age≥65
老年2型糖尿病患者血清炎症因子水平及其与大血管病变的相关性
