单纤维肌电图对糖尿病周围神经病的诊断价值
王真真;陈文明;卢祖能;王镇涛;曾庆杏;聂传云
【期刊名称】《中国组织工程研究》 【年(卷),期】2003(007)007
【摘要】Aim To study the clinical significance of single fiber electromyography(SFEMG)
in
diabetic
peripheral
neuropathy(DPN).Methods 36 patients with type 2 diabetes mellitus were investigated, in which the values of jitter and fiber density(FD) of extensor digitorum communis muscle (EDC) were determined by Viking IV,meanwhile,conventional
nerve
conduction
studies(NCS)
were
performed,and fasting blood glucose and glycosylated hemoglobin A1C(HbA1C) was measured.Results The values of jitter were associated with FD, and both jitter and FD were positively related to HbA1C.18 cases with abnormal NCS showed increased jitter in 18( with block in 11)and increased FD in 14.18 cases with normal NCS showed,increased jitter in 7(with block in 3) and increased FD in 5.Conclusion Denervation- reinnervation reflected by jitter and FD was associated with the metabolic status.SFEMG could be served as sensitive means to early diagnosis of DPN, and may detect subclinical neuropathy.%目的探讨单纤维肌电图 (SFEMG)在糖尿病周围神经病 (DPN)中的应用.方法 2型糖尿病患者 36例,采用 Viking IV肌电图仪,测定指总伸肌的颤抖和纤维密度 (FD),同时进行常规神经传导检测 (NCS)并测量空腹血糖和糖化血红蛋白 (HbA1c).结果
单纤维肌电图对糖尿病周围神经病的诊断价值
