康莱特注射液联合洛铂治疗非小细胞肺癌恶性胸腔积液的
临床研究
莫安薇;麦泽锋;王燕艳;纪小珍
【期刊名称】《现代药物与临床》 【年(卷),期】2019(034)004
【摘要】Objective To explore the efficacy of Kanglaite Injection combined with luoplatin in treatment of non-small cell lung cancer with malignant pleural effusion. Methods Patients (108 cases) with non-small cell lung cancer concurrent malignant pleural effusion in Hainan General Hospital from February 2016 to March 2018 were randomly divided into control and treatment groups, and each group had 54 cases. Patients in the control group were intrapleural injection administered with Lobaplatin for injection, 30 mg/m2 added into 5％ glucose injection 50 mL. Patients in the treatment group were intrapleural injection administered with Kanglaite Injection on the basis of the control group, 100 mL/time, once daily. Patients in two groups repeated once after 21 d, and were treated for 2 times.After treatment, the clinical efficacy was evaluated, and the VEGF and RCAS1 expression levels in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups was 70.4％ and 87.0％respectively, and there were differences between two groups (P<0.05). After treatment, the VEGF and RCAS1 levels in
康莱特注射液联合洛铂治疗非小细胞肺癌恶性胸腔积液的临床研究
