血管回声跟踪技术定量评价系统性红斑狼疮患者颈动脉弹
性功能
王芹秀;雷成功;郭艳琴;茹晋丽;张改连;李海文
【期刊名称】《中华风湿病学杂志》 【年(卷),期】2010(014)005
【摘要】Objective To explore the clinical value of early diagnosis of atherosclerosis in patients with systemic lupus erythematosus (SLE) using vascular echo-tracking technique and to detect changes of elastieity of carotid artery quantitatively in SLE patients.Methods Fifry patients with SLE were divided into SLE1 group(duration≤1 year),and SLE2 group(duration>1 year)based on different course.An ultrasonic echo-tracking method was used to measure patients'pressure strain elastic
modulus
(Ep),the
stiffness
constant(β),arterial
compliance(AC),augmentation index(AI),pulse wave velocity (PWVβ) and intimamedia thickness(IMT)of the common carotid arteries in 50 patients with SLE and in 25 healthy control subjects.Results Among carotid artery elasticity indicators of three groups,there was no significant difference in AI(P>0.05).Ep,β,PWVβ parameters of SLE1 group and SLE2 group were statistically higher than that of the control group[Ep
of
SLE1
group,SLE2
group,control
group
was
(69±20),(103±40),(48±18)kPa respectively;β was 5.2±1.9,8.0±3.1,4.2±1.3 respectively;PWVβ was 5.2±0.7,6.3±1.1,4.5±0.7]respectively,but AC(AC
血管回声跟踪技术定量评价系统性红斑狼疮患者颈动脉弹性功能
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