Knockdown of flotillin-2 inhibits lung surfactant secretion by alveolar type Ⅱ cells

Knockdown of flotillin-2 inhibits lung surfactant

secretion by alveolar type Ⅱ cells

Narendranath Reddy Chintagari;Deming Gou;Lin Liu

【期刊名称】《细胞研究（英文版）》 【年(卷),期】2008(018)006

【摘要】@@ Dear Editor,rnLung surfactant is stored in lamellar bodies and exocytosed following fusion of the lamellar bodies with the plasma membrane of alveolar type Ⅱ (AT2) cells [1].A number of proteins have been shown to be involved in surfactant secretion including SNAREs,NSF,α-SNAP and annexin A2 [2,3].Lipid rafts enriched in SNAREs are crucial for surfactant secretion [4]. 【总页数】3页(701-703) 【关键词】

【作者】Narendranath Reddy Chintagari;Deming Gou;Lin Liu

【作者单位】Department of Physiological Sciences,Oklahoma State University,264 McElroy Hall,Stillwater,OK 74078,USA;Department of Physiological

Sciences,Oklahoma

State

University,264

of

McElroy

Hall,Stillwater,OK 74078,USA;Department Physiological

Sciences,Oklahoma State University,264 McElroy Hall,Stillwater,OK 74078,USA 【正文语种】中文 【中图分类】Q2

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