可注射性硫酸钙在兔椎体松质骨中成骨性能的研究
华俊;孙永明;刘栋;沈忆新;冯一中
【期刊名称】《中国血液流变学杂志》 【年(卷),期】2011(021)003
【摘要】Objective To investigate biodegradation and bone formation of injectable calcium sulfate in rabbit spongy bone.Method Eighteen rabbits were randomly divided into 2 groups,A and B.Osseous defeats were created in lumbar bodies using a drill,resulting in a 3.2mm diameter *5mm deep cavity.The prepared material(CSC) was injected into cavities in group A,group B was untreated as blank control,their general and local reactions in implanted regions were observed. The bone formation and degradation were observed in 2,6 and 12 weeks by macroscopically,microscopically,x-rays and tissue slices.Photographs were selected in each group at each time points for computer software processing to calculate the percentages of bone in the images of postoperative slices.Results All rabbits were recovered within 1 day following the procedure,wounds healed in a routine manner, and there were no inflammatory response.Photographs at 2,6,12 weeks demonstrated progressive,resorption of CSC and replacement by bone.At
12
weeks,the
stained
show
has
completely
resorbed,thickened;interconnected trabeculae and newly wove bone were seen. The bone percentage in group A was significantly higher
可注射性硫酸钙在兔椎体松质骨中成骨性能的研究
