Ti6Al4V-AlTiN涂层材料的急性毒性试验*◆
朱维东1，朱 涛1，王旭东2，蒋耀光3 【摘 要】摘要
【期刊名称】中国组织工程研究 【年(卷),期】2010(014)025 【总页数】3
【关键词】急性毒性试验；AlTiN涂层；Ti6Al4V合金；高度离子化脉冲工艺；小鼠
Supported by:Guizhou Provincial Science and Technology Project,No. 20082004*
BACKGROUND: AlTiN ceramic coatings have many advantages such as high hardness, excellent wear properties, good chemical inertness and strong adhesion, which are all consistent with the characteristics of bio-ceramics. To achieve the clinical safety, a comprehensive evaluation of acute toxicity AlTiN coating is needed.
OBJECTIVE: To test acute toxicity of Ti6Al4V-AlTiN coating materials, and to provide a reference for long-term toxicity and other toxicological tests.
METHODS: The mouse left and right femoral quadriceps muscle was injected with aseptic Ti6Al4V-AlTiN coating material, the general condition and reaction on the injection site of animals were observed at 14 days after injection, normal saline served as the negative control.
Ti6Al4V-AlTiN涂层材料的急性毒性试验
