全凭静脉麻醉中年龄对顺式阿曲库铵药效学的影响
高飞宇;徐惠青
【期刊名称】《中国医药》 【年(卷),期】2013(008)0z1
【摘要】Objective To evaluate the effect of age on pharmacodynamics of cisatracurium in total intravenous anesthesia.Methods Foay patients with lumbar vertebra internal fixation surgery under total intravenous anesthesia were divided into group Ⅰ and Ⅱ with 20 cases in each group.Under TOF stimulation monitoring,cisatracurium 0.15 mg/kg was infected and tracheal intubation was performed when TOF being zero.When T1 restored to 5％,cisatracurium 0.05 mg/kg(injected within 5 s each time) was injected at irregular intervals.The intubation conditions and the pharmacodynamcs of cisatracurium were evaluated.Results Intubation conditions of the onset time and recovery index were not significantly different between the two groups.The clinical effective time and recovery to 25％ and 75％ time was(42 ±5),(52 ±7),(66 ± 13)min,and group]Ⅱ was(40 ±5),(49 ±5),(62 ± 11) min,the group Ⅰ was longer than group Ⅱ.Each clinical effective time of the four times additional drugs in group Ⅰ was longer than that in group Ⅱ.There was no notable difference on that between the two groups.Cisatracurium average dosage was less in group Ⅰ [(3.5 ± 1.3) μg/(min · kg)] than that in group Ⅱ [(4.6 ± 1.5) μg/(min · kg)] (P ＜
全凭静脉麻醉中年龄对顺式阿曲库铵药效学的影响
