丙种球蛋白治疗重症手足口病疗效观察
李明;苏维
【期刊名称】《蚌埠医学院学报》 【年(卷),期】2015(000)004
【摘要】Objective:To explore the curative effects of intravenous immunoglobulin( IVGV) in the treatment of the sever hand-foot-mouth disease(HFMD). Methods:Forty-two clildren with sever HFMD were divided into the conventional therapy group(20 cases) and immunoglobulin therapy group( 22 cases ) . The immunoglobulin therapy group included 14 cases treated with single immunoglobulin (single therapy group) and 8 cases treated with immunoglobulin combined with methylprednisolone(combination therapy group). The curative
effects
between
three
groups
were
compared.
Results:Compared with the conventional therapy group, the times of body temperature recovery, deflorescence and nervous system symptom improvement in the combination and single therapy groups were significantly shorter(P<0. 01). The invalid or progress for the critical illness in 7 cases in the conventional therapy group,no invalid or progress case in the combination therapy group, and progress for the critical illness in 1 case in single therapy group were found. Compared with the conventional therapy group,the failed or progress case in single therapy group was less(P<0. 05). Conclusions:The IVGV treatment