以小脑性共济失调为主要临床表现的神经白塞病
Liu Zheng;Dong Huiqing;Su Shengyao;Song Xiaodong;Wang Jingsi;Wu Yan;Li Dawei;Qiu Zhandong
【期刊名称】《脑与神经疾病杂志》 【年(卷),期】2019(027)005
【摘要】Objective? To explore the clinical, radiological features and treatment of neuro-Behcet disease presenting chronic progressive cerebellar ataxia and atrophy.Method An rare case of a 27-year-old female with neuro-Behcet disease presenting chronic progressive cerebellar ataxia and atrophy was reported. Her clinical presentation, potential pathophysiology and treatment were discussed. The related literatures have been reviewed. Results? The patient presented with slightly scanning speech, symmetric limb and trunk ataxia for 12 years. Besides, she developed recurrent oral ulcer, skin suppurative papules perineal ulcer, eyelid granuloma, and heart damage. Neurological examination found bilateral horizontal nystagmus in all directions, mildly decreased muscle tone, dysmetria while performing right-sided finger-nose and heel-knee-shin tests and unbalanced tandem gait. Serological tests for related immunological disease were negative. Cerebral MRI revealed atrophy of cerebellar hemisphere and vermis. She was diagnosed as special variant of neuro-Behcet disease presenting chronic progressive cerebellar ataxia and atrophy. Conclusion Neuro-
以小脑性共济失调为主要临床表现的神经白塞病
