RAPID TEST FOR CELLULAR FIBRONECTIN
申请(专利)号： US202016876994
专利号： US2020284799A1 主分类号： G01N33/68
申请权利人： PREDICTION
BIOSCIENCES S.A.S. 公开国代码： US 优先权国家： IB;
US
摘 要：
The present invention relates to a rapid assay for detection of human cellular fibronectin (c-Fn) where ELISA-based assays have previously been developed for detecting and measuring cellular fibronectin in biological fluids, but these methods are too time-consuming for practical clinical diagnostic use. The assay of the present invention enables prediction of bleeding events on a rapid timescale. Described as well are high affinity human monoclonal antibodies, particularly those directed against isotopic determinants of cellular fibronectin (c-Fn), as well as direct equivalents and
derivatives of these antibodies. These antibodies bind to their respective target
申请日： 2020-05-18 公开公告日： 2020-09-10
分类号： G01N33/68;
C07K16/18; C07K7/08; C07K14 发明设计人： CORNELIUS
DIAMOND 申请国代码： US
优先权： 20200518 US
202016876994; 20141010 US 201414391883; 20130411 IB 2013001164; 20120413 US 201213506357
摘 要 附 图：
with an affinity at least 100 fold greater than they do to plasma fibronectin, and enable assays to be created that detect c-Fn in less than 30 minutes in a variety of detection formats, and in some detection formats less than 15 minutes. These antibodies are useful for diagnostics, particularly prediction of bleeding events, prophylaxis and treatment of disease. 主权项：
权 利 要 求 说 明 书
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RAPID TEST FOR CELLULAR FIBRONECTIN
