动态血糖监测系统和胰岛素泵在ICU糖尿病患者的联合应
用
黄文龙;张晓兰;方铭;刘云
【期刊名称】《江苏医药》 【年(卷),期】2011(037)003
【摘要】Objective To investigate the therapeutic outcomes of continuous glucose monitoring system(CGMS) and continuous subcutaneous insulin infusion pump system(CSⅡ) in type 2 diabetes mellitus(T2DM) patients with critical condition in intensive care unit(ICU). Methods A total of 120 T2DM patients in ICU was randomly divided into three groups with 40 cases each. CGMS combined with CSⅡ was used in group A, CSⅡ alone in group B and repeated injection of insulin therapy in group C. The capillary blood glucose of finger tip was monitored in groups of B and C. The changes of fasting blood glucose(FBG), mean amplitude of glycemic excursions (MAGE) and the number of hypoglycemia events were recorded and compared among three groups after for treatment 7 days.Results After pump therapy for 7 days, the whole day glucose, MBG and MAGE were all significantly lower in groups of A and B than those before treatment(P＜0. 05), which were lower in group A than those in group B(P＜0. 05). The mean blood glucose(MBG), mean amplitude of glucose fluctuation(MAGF) and hypoglycemia events of group A were obviously less than those in
group B (P＜0.05). Conclusion CGMS can depict a continuous blood glucose curve,discover hyperglycemia or hypoglycemia events. CGMS combined with CSII is more beneficial to the glucose control in the critical T2DM patients in ICU.%目的 探讨动态血糖监测系统(CGMS)和胰岛素泵持续皮下注射治疗(CSII)在重症监护病房(ICU)2型糖尿病(T2DM)患者的应用效果.方法 将120例T2DM患者随机均分为三组:A组采用CGMS与CSII结合治疗模式(40例),B组采用单纯CSII治疗(40例),C组采用胰岛素多次注射治疗(40例).后两组采用指端毛细血糖监测法.治疗7 d后比较三组血糖控制情况、血糖达标率及血糖漂移情况.结果 治疗7 d后,A组和B组患者的全日血糖、平均血糖(MBG)、平均血糖波动幅度(MAGF)均较治疗前明显下降,且明显优于C组(P<0.05),低血糖发生次数亦较C组明显减少(P<0.05).其中,A组MBG、MAGE、低血糖次数均显著低于B组(P<0.05).结论 CGMS能监测血糖连续的变化曲线,及时发现高血糖和低血糖,与胰岛素泵联合治疗更有利于ICU糖尿病患者血糖的控制,降低低血糖的发生率. 【总页数】3页(287-289)
【关键词】2型糖尿病;动态血糖监测系统;胰岛素泵 【作者】黄文龙;张晓兰;方铭;刘云
【作者单位】214400,江阴市人民医院内分泌病科;214400,江阴市人民医院内分泌病科;214400,江阴市人民医院内分泌病科;南京医科大学第一附属医院老年内分泌病科 【正文语种】中文 【中图分类】R598
【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_jiangsu-medical-journal_thesis/0201249103556.html 【相关文献】
1.动态血糖监测系统和胰岛素泵在ICU糖尿病患者的联合应用 [J], 王成连 2.动态血糖监测系统联合胰岛素泵在老年2型糖尿病患者中的应用效果 [J], 傅明捷; 黄萍; 廖淑金; 苏咏明; 王艳
3.实时动态血糖监测联合胰岛素泵与回顾性动态血糖监测联合胰岛素泵在2型糖尿病患者治疗中的优势探讨 [J], 吴东红; 梁桂敏; 柳杰; 徐滨华; 陈婧; 刘大娜; 马晶
4.罗格列酮配合胰岛素泵与单纯胰岛素泵治疗对2型糖尿病患者血糖及胰岛素抵抗的影响研究 [J], 胡加鹏; 胡玮谦
5.动态血糖监测联合胰岛素泵治疗对2型糖尿病患者生活质量的影响 [J], 李春华
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动态血糖监测系统和胰岛素泵在ICU糖尿病患者的联合应用
