Impact of weight gain following smoking cessation on one-yearoutcome after drug-eluting st

Impact of weight gain following smoking cessation on one-yearoutcome after drug-eluting stent

implantation

FAN Xiao-ming;L(u) An-kang;SHEN Wei-feng;WU Qi-hong;MA Xiao-ye;YANG Er-li;ZHANG Rui-Yan;ZHANG Shi-jia

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2012(125)006

【摘要】Background Weight gain following smoking cessation increases cardiovascular risk,but its effects on prognosis after percutaneous coronary intervention (PCI) remain unclear.This study aimed to investigate the relationship between weight gain post smoking cessation and one-year clinical outcome in patients who underwent PCI with drug-eluting stent (DES).Methods A total of 895 consecutive male smoking patients were divided into quitters (n=437) and continuers (n=458)according to their smoking status after PCI.Weight gain,major adverse cardiac events (MACE,including cardiac deaths,myocardial infarction and revascularization),and recurrent angina were recorded during follow-up for one year.Results Average weight gain in quitters was more than that in continuers (1.5 kg vs.-0.03 kg,P＜0.001).Weight was unchanged or increased by more than 1.5 kg in 78.17％ of continuers,while 50.57％ of quitters had a weight gain of less than 1.5 kg.Compared with continuers,MACE in quitters was significantly