烧伤患者血小板微粒的变化及临床意义
唐佳俊;郇京宁
【期刊名称】《中华创伤杂志》 【年(卷),期】2012(028)010
【摘要】Objective To investigate the clinical significance of changes of platelet
microparticles
(PMPs)
in
burn
and
burn
infection
patients.Methods The patients were divided into burn shock group (n =44),burn infection group (n =33) and control group (n =11 ).Plasma PMPs were determined by flow cytometry and were recorded in absolute value and in particle proportion.Also,the frequently used biochemical indicators were detected and analyzed for their relationship with PMPs.Results CD41 + PMPs levels in the burn shock and burn infection groups were higher than those in the control group (P ＜ 0.01 ) and they showed positive relation with extent of burn ( r =0.258,P ＜ 0.05
).Stepwise
regression
analysis
of
indicated burn
and
that
r-
glutamyltranspeptidase (r-GT),extent alanine
aminotransferase (ALT) entered CD41 + PMPs level regression equation.Conclusion The increase of PMPs levels may be closely correlated with the pathological coagulation state in severe burn patients.%目的 探讨烧伤和烧伤感染患者血小板微粒( platelet microparticles,PMPs)的变化及临床意义. 方法 选择烧伤休克期组(44例)、烧伤感染组(33例)和对照组(11例)患者,用流式细胞仪等方法检测血浆中PMPs水
烧伤患者血小板微粒的变化及临床意义
