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ANTI-DEPRESSIVE ACTIVITY

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ANTI-DEPRESSIVE ACTIVITY

申请(专利)号: ZA19760001386

专利号: ZA761386B 主分类号: C07C 申请权利人: PHILIPS NV 公开国代码: ZA 优先权国家: NL

摘 要:

The novel compounds of formula I wherein R is hydrogen, methyl or

chlorine, R1 is oxygen or sulphur, R2 is OCH2, CH20CH2, OC2H40CH2, R3 is hydrogen or methyl, n and p are 0 or 1 and n + p is 0 or 1 and salts thereof have a very powerful anti-depressive activity which for a considerable part, and in some substances even entirely, is based on serotonine potentiation. Monoamino oxidase inhibition does not contribute to the anti-depressive effect. The

substances have a low toxicity and are substantially free from side effects. The compounds can be synthesized and processed to compositions according to known methods. 主权项:

申请日: 1976-03-08 公开公告日: 1977-10-26

分类号: C07C 发明设计人: WELLE H;

CLAASSEN V 申请国代码: ZA

优先权: 19750320 NL

7503307

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ANTI-DEPRESSIVE ACTIVITY

ANTI-DEPRESSIVEACTIVITY申请(专利)号:ZA19760001386专利号:ZA761386B主分类号:C07C申请权利人:PHILIPSNV公开国代码:ZA优先权国家:NL摘要:ThenovelcompoundsofformulaIwhereinRishydrog
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