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慢阻肺肺心病心衰患者的美托洛尔治疗效果分析
作者:于爽
来源:《中外医疗》2015年第26期
[摘要] 目的 探究美托洛尔治疗慢性阻塞性肺疾病(COPD)肺心病心力衰竭的疗效及观察其安全性。方法 整群选取2014年1月—2015年1月在该院收治的COPD肺心病心力衰竭的患者88例,采用随机的方法将其分为观察组和对照组,每组44例。对照组采用常规治疗,观察组在对照组的基础上加用美托洛尔,在患者治疗前与治疗后16周分别记录右心室舒张期内径(RV)、肺动脉收缩压(PASP)、静息心率(RHR)。结果 两组治疗前后心力衰竭情况中观察组与对照组的有效率,差异无统计学意义(P>0.05),对照组室性期前收缩(4879±723)次,较观察组的(1795±374)次严重,差异有统计学意义(P
[关键词] 美托洛尔;慢性阻塞性肺疾病;肺心病心力衰竭;疗效;安全性
[中图分类号] R541.5 [文献标识码] A [文章编号] 1674-0742(2015)09(b)-0137-03 [Abstract] Objective To explore metoprolol in the treatment of chronic obstructive pulmonary disease (COPD) Cor heart failure and the observed safety. Methods January 2014 --2015 in January of COPD patients admitted to hospital with heart failure of 88 cases of lung, using a random approach will be divided into two groups and the control group 44 cases. Control group with
conventional treatment, observation group in the control group based on the use of metoprolol in patients before treatment and after 16 weeks of treatment were recorded right ventricular diastolic diameter (RV), pulmonary artery systolic pressure (PASP), resting Heart Rate (RHR). Results There are two groups before and after the treatment of heart failure cases in the observation group and the control group of five significant difference in efficiency (P> 0.05), Control room before contraction(4879±723) times, compared with the observation group (1795±374) times severe, with significant difference (P
[Key words] Metoprolol; Chronic obstructive pulmonary disease; Pulmonary heart failure; Efficacy; Safety
心力衰竭患者中很大一部分人合并慢性阻塞性肺疾病(COPD)[1]。慢性心力衰竭患者通常伴有其他心脏疾病,对心肌的射血功能造成影响,心室的充盈状态出现异常,影响心肌血运状态[2]。美托洛尔是一种β1受体阻滞剂,其具有较高选择性,近年来在防治心血管疾病中具有重大意义,特别是在治疗慢性心力衰竭时具有重要作用,然而β受体阻滞剂可增加气道阻力,严重时威胁患者生命安全,从而在治疗慢性阻塞性肺疾病(COPD)肺心病心力衰竭时受到阻碍[3]。该研究中整群选用2014年1月—2015年1月在该院收治COPD肺心病心力衰竭的