PYRAZOLE DERIVATIVES FOR TREATING HIV
申请(专利)号: BG20030108244
专利号: BG108244A 主分类号: C07D231/18
申请日: 2003-10-08 公开公告日: 2005-04-30
分类号: C07D231/18;
申请权利人: 公开国代码: 优先权国家: 摘 要:
PFIZER INC.
BG IB;
GB
发明设计人: 申请国代码: 优先权: 摘 要 附 图:
C07D231/20; C07D403/06; C07D413/06; C07D401/12; C07D405/12; C07D403/04; C07D498/04; C07D401/06; C07D471/04; A61K31/415; A61K31/4162; A61K31/4155; A61P31/18 JONES LYN;
MOWBRAY CHARLES; PRICE DAVID;
SELBY MATTHEW; STUPPLE PAUL BG
20010410 GB
0108999; 20011115 GB 0127426; 20020404 IB 0201234
This invention relates to pyrazole derivatives of the formula of
pharmaceutically acceptable salts,
solvates or derivatives thereof, wherein R1 to R4 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such compounds of the present invention are useful in the treatment of a variety of disorders
including those in which the inhibition of the reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodeficiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS). 主权项:
ПАТЕНТНИ ПРЕТЕНЦИИ/n1. Съединение с формула (I) или негова фармацевтично приемлива сол, солват или п
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