腹腔热灌注化疗联合内生场热疗治疗发复性卵巢癌的临床
观察
贾惠
【期刊名称】《肿瘤研究与临床》 【年(卷),期】2009(021)008
【摘要】目的 评估腹腔热灌注化疗联合内生场热疗对晚期复发性卵巢癌的疗效.方法 22例晚期复发卵巢癌患者注入预热的氯化钠溶液(Ns)+顺铂(DDP)+依托泊苷(VP16),同时采用NRL-002内生场热疗机热疗60～120 min,每周热灌注化疗1次,单纯热疗1次.结果 总有效率(CR+PR)63.6%,CA125明显下降,CD4/CD8比值及NK细胞数较治疗前升高,临床受益反应81.8%,中位疾病进展时间(MTTP)及中位生存时间(MST)分别为7.8个月和18.5个月.结论 腹腔热灌注化疗联合内生场热疗治疗晚期复发性卵巢癌疗效确切,能改善患者的生活质量,不良反应轻,值得临床推广.%Objective To study the efficacy of intraperitoneal
chemohyperthermia
with
Double
RF
Tumor
Hyperthermia System on recurrent ovarian cancer. Methods 22 cases of advanced recurrent ovarian cancer were infused with hot NS and DDP and VP16 in abdominal cavity, NRL-002 double RF Tumor Hyportherrnia System was applied to heat the abdominal part for 60-120 minutes. RF hyperthermia was given twice per week and chemotherapy once per week. Results The overall response rate (CR+PR) was 63.6%. The serum CA125 ratio was decreased significantly. The level of CD4/CD5 and NK cells was higher than that of pretherapy after management. The clinical
beneficial response(CBR) was 81.8%. The median TIP and MST were 7.8 mouth and 18.5 month. Conclusion Intraperitoneal ehemohyporthermia with NRL-002 Double RF Tumor Hyperthermia System was an effective way to treat advanced recurrent ovarian cancer. It Can also improve life quality of patients with mild adverse effect and recommended to be applied clinically. 【总页数】2页(469-470)
【关键词】卵巢肿瘤;肿瘤复发,局部;腹腔温热化疗;预后 【作者】贾惠
【作者单位】271000,山东省泰安市肿瘤防治院妇瘤科 【正文语种】中文 【中图分类】R73 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_cancer-research-clinic_thesis/0201236930744.html 【相关文献】
1.先期化疗联合术后腹腔热灌注化疗治疗晚期卵巢癌效果观察 [J], 王沛; 赵晓华; 王晓燕
2.腹腔内贝伐珠单抗联合腹腔热灌注化疗治疗卵巢癌腹腔积液的临床观察 [J], 赵辉; 杜楠; 王海滨; 孙君重; 陈殿君; 范忠义; 李晓松; 付艳; 康欢荣
3.静脉化疗联合高精度持续循环腹腔热灌注化疗治疗卵巢癌的疗效观察 [J], 郭亚琼
4.高精度持续循环腹腔热灌注化疗联合静脉化疗治疗卵巢癌的临床研究 [J], 崔欢; 张菊新
5.重组人血管内皮抑制素联合静脉化疗和腹腔热灌注化疗治疗晚期卵巢癌的临床研究 [J], 吴素芳; 谢优优; 陈佩芳
以上内容为文献基本信息，获取文献全文请下载
腹腔热灌注化疗联合内生场热疗治疗发复性卵巢癌的临床观察
