乳腺癌化疗相关认知障碍的前瞻性记忆损害的特征
程怀东;陈婵娟;杨震;张明军;陈振东;汪凯
【期刊名称】《临床肿瘤学杂志》 【年(卷),期】2012(017)011
【摘要】目的 探讨乳腺癌患者出现化疗相关认知障碍(CICI)中基于事件的前瞻性记忆(EBPM)和基于时间的前瞻性记忆(TBPM)损害的特征.方法 分别建立EBPM和TBPM的神经心理学测验方法,选取27例乳腺癌术后辅助化疗患者(观察组)以及年龄、教育程度相匹配的30例健康者(对照组)进行测试,记录两组数据并比较.结果 观察组的EBPM得分为1.11 ±1.09,明显低于对照组的2.23 ±0.77(P ＜0.01)；观察组和对照组的TBPM得分分别为4.33±1.24和4.83±1.09,差异无统计学意义(P＞0.05).结论 乳腺癌患者出现CICI中存在前瞻性记忆损害,主要表现为EBPM损害,而TBPM损害不明显.%Objective To investigate the event-based prospective memory ( EBPM) and time-based prospective memory (TBPM) disorders associated with chemotherapy-induced cognitive impairment in patients with breast cancer. Methods Twenty-seven cases with breast cancer who underwent adjuvant chemotherapy after operation, and 30 healthy women with matched age and education level were administered with a neuropsychological batter)' of tests including EBPM and TBPM tasks. Results The EBPM score of breast cancer patients and healthy controls were 1.11 ± 1. 09 and 2. 23 ± 0. 77 , with significant differences ( P < 0. 001 ). The TBPM score of breast cancer patients and healthy controls
乳腺癌化疗相关认知障碍的前瞻性记忆损害的特征
