多原发结直肠癌168例临床分析
蔡宏;董锐增;吴江宏;朱蕙燕;王亚农;师英强;莫善兢
【期刊名称】《中华外科杂志》 【年(卷),期】2008(046)005
【摘要】Objective To study the incidence rate of multiple primary colorectal carcinomas (MPCC)in colorectal carcinoma and to evaluate its clinical and pathological characteristics.Methods One hundred and sixty-eight(4.6％)patients from 3663 cases with colorectal carcinoma were diagnosed with MPCC from January 1985 to December 2003.The clinical data of the patients were collected retrospectively to investigate the diagnosis and treatment of MPCC.Results Of the 168 patients，81 were diagnosed as svnchronous colorectal carcinoma(SC)，72 with metachronous colorectal carcinoma(MC)，15 with both SC and MC.The median age at time of diagnosis of colorectal carcinoma was 58 years old(range from 20 to 82 vears old).Three hundred and ninety-three cancer lesions were detected in these 168 cases(mean，2.3 lesions/case).The rectum and sigmoid colon were the most involved sites(61.6％).Eighteen cases (10.7％)were verifled with hereditary non-polyposis colorectal cancer(HNPCC)while another 9 cases were highly suspected.Fourteen patients(8.3％)were found with other malignancies out of large intestine， 41 patients(24.4％)with coloreetal adenomas，72(42.9％)with adenoma carcinogenesis.Among the 96 SC patients,91
多原发结直肠癌168例临床分析
