Sources of multidrug-resistant Acinetobacter baumannii and its role in respiratory tract c

Sources of multidrug-resistant Acinetobacter baumannii and its role in respiratory tract colonization and nosocomial pneumonia in

intensive care unit patients

HUANG Jie;CHEN Er-zhen;QU Hong-ping;MAO En-qiang;ZHU Zheng-gang;NI Yu-xing;HAN Li-zhong

【期刊名称】《中华医学杂志（英文版）》 【年(卷),期】2013(126)010

【摘要】Background Multidrug-resistant Acinetobacter baumannii (MDRAB) is an important and emerging hospital-acquired pathogen worldwide.This study was conducted to identify the sources of MDRAB and its role in respiratory tract colonization and nosocomial pneumonia in intensive care unit (ICU) patients.Methods We conducted a prospective active surveillance study of MDRAB in three ICUs at a Chinese Hospital from April to August 2011,to identify the sources of MDRAB and its role in respiratory tract colonization and nosocomial pneumonia.Results One hundred and fourteen (13.0％) MDRAB isolates were detected from 876 specimens,with a sensitivity of 11.6％ (55/474) in screening of the pharyngeal and tracheal swabs,and 14.7％ (59/402) of the sputum/endotracheal aspirates.MDRAB colonization/infection was found in 34 (26.8％) of 127 patients,including 16 (12.6％) cases of pure colonization and 18 (14.2％) cases of pneumonia (two pre-ICU-