支气管镜肺泡灌洗联合无创通气治疗重症肺炎合并呼吸衰
竭的疗效观察
卢滨;吴红科;姚菲菲;张翠翠
【期刊名称】《广西医科大学学报》 【年(卷),期】2024(035)001
【摘要】Objective:To investigate the clinical effect of bronchoalvoelar lavage (BAL) combined with noninvasive ventilation on respiratory failure in severe pneumonia patients.Methods:80 severe pneumonia patients with respiratory failure treated in our hospital from January 2013 to June 2016 were enrolled and were randomly divided into an observation group and a control group,with 40 cases in each group.Patients in the control group received noninvasive positive-pressure ventilation,and those in the observation group were treated as the control group with addition of BAL.The total response rate,pulmonary function,blood gas and inflammatory factors levels were observed and compared.Results:The response rate in the observation group was significantly higher than that in the control group (P＜0.05).Compared with the control group,the PaO2,SaO2,FEF25％-75％,and DLCO were obviously increased,while the levels of high-mobility group box 1 protein (HMGB-1) and soluble triggering receptor expressed on myeloid cell-1 (sTREM-1) in serum were decreased in the observation group (P＜ 0.05).Conclusion:BAL combined with
支气管镜肺泡灌洗联合无创通气治疗重症肺炎合并呼吸衰竭的疗效观察
