支气管肺泡灌洗液联合TCT在周围型肺癌诊断中的应用
郑亮;亓玉心;周玉法
【期刊名称】《现代肿瘤医学》 【年(卷),期】2017(025)010
【摘要】目的:探讨支气管肺泡灌洗液联合TCT在周围型肺癌诊断中的应用价值.方法:纳入2014年12月至2015年12月收治的123例周围型肺癌患者,所有患者支气管镜检查未发现病灶,遂同时获得支气管肺泡灌洗液和支气管镜刷片标本,同时采用TCT和直接涂片法检测,比较四种方法的敏感度.并对支气管镜检查结果与术后病理结果进行比较,分析支气管镜检查结果的特异性.结果:支气管肺泡灌洗液联合TCT的敏感度显著高于支气管肺泡灌洗液直接涂片法检测的敏感度(36.6% vs 17.9%,P<0.05);支气管镜刷片联合TCT的敏感度亦显著高于支气管镜刷片直接涂片法检测的敏感度(14.6% vs 8.1%,P<0.05);而且四种方法中支气管肺泡灌洗液联合TCT的敏感度最高(P<0.05).支气管镜检查结果与术后手术组织病理结果比较的特异性为100%.支气管肺泡灌洗液联合TCT的分类诊断和手术病理组织学诊断的符合率为84.4%.结论:支气管肺泡灌洗液联合TCT能提高周围型肺癌的检出诊断率,支气管肺泡灌洗液联合TCT可推广应用于临床.%Objective:To investigate the value of bronchoalveolar lavage fluid combined with ThinPrep cytology test(TCT) in the diagnosis of peripheral lung cancer.Methods:The data of one hundred and twenty-three patients diagnosed with peripheral lung cancer were recruited from December 2014 to December 2015.No lesions had been found in bronchoscope examinations of all patients.Therefore,bronchoalveolar
lavage fluid and blind bronchial brushing specimen were been obtained in all patients.TCT and direct smear assay were conducted for all specimens.The sensitivity of four cytology methods was compared.The specificity of bronchoscopy cytology was analyzed.Results:The sensitivity of bronchoalveolar lavage fluid combined with TCT was significantly higher than that of bronchoalveolar lavage fluid direct smear assay(36.6% vs 17.9%,P<0.05),while the sensitivity of blind bronchial brushing combined with TCT was significantly higher than that of blind bronchial brushing direct smear assay(14.6% vs 8.1%,P<0.05).Moreover,the sensitivity of bronchoalveolar lavage fluid was higher than the other 3 methods(P<0.05).The specificity of bronchoscopy cytology were 100%.The coincidence of bronchoalveolar lavage fluid combined with TCT and surgical pathology were 84.4%.Conclusion:Bronchoalveolar lavage fluid combined with TCT is more valuable in the diagnosis of peripheral lung cancer and can be widely used in clinical. 【总页数】3页(1572-1574)
【关键词】支气管肺泡灌洗液;TCT;周围型肺癌 【作者】郑亮;亓玉心;周玉法
【作者单位】莱芜市人民医院呼吸内科,山东 莱芜 271100;莱芜市人民医院呼吸内科,山东 莱芜 271100;莱芜市人民医院呼吸内科,山东 莱芜 271100 【正文语种】中文
【中图分类】R734.2 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_journal-modern-oncology_thesis/0201236357703.html 【相关文献】
1.支气管肺泡灌洗液联合气管镜刷片对周围型肺癌的诊断价值 [J], 阮玉姝; 陈世雄; 高宝安; 官莉; 向光明; 张婷婷
2.选择性定位支气管肺泡灌洗液联合气管镜刷片细胞学检查对周围型肺癌的诊断价值 [J], 邰力艾提·阿不都热依木; 白合尼沙·阿不都热西提; 德力夏提·依米提 3.选择性定位的支气管肺泡灌洗液配合气管镜刷片细胞学检查对周围型肺癌的诊断价值 [J], 宋明进; 郝东
4.支气管肺泡灌洗液配合气管镜刷片细胞学检查对周围型肺癌的诊断效果及价值观察 [J], 柳小平; 李淑华
5.支气管肺泡灌洗液液基细胞学检查在周围型肺癌诊断中的价值 [J], 朱建勇; 曾玉琴; 邝军; 王永兰; 张立波; 何敏
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支气管肺泡灌洗液联合TCT在周围型肺癌诊断中的应用
