舟山市普陀区人群尿碘与摄食盐碘的相关性分析
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[摘要] ............................................................................................................................... 1 [Abstract] .......................................................................................................................... 2 1前言 ............................................................................................................................... 3 2 实验材料、主要仪器与试剂 ...................................................................................... 4
2.1 实验材料 ............................................................................................................ 4 2.2 主要仪器 ............................................................................................................ 4 2.3 主要试剂 ............................................................................................................ 4 3 实验方法 ...................................................................................................................... 5
3.1 尿碘的测定方法 ................................................................................................ 5
3.1.1配制溶液 ................................................................................................... 5 3.1.2操作步骤 ................................................................................................... 5 3.2盐碘的测定方法 ................................................................................................. 6
3.2.1硫代硫酸钠标准液的标定 ....................................................................... 6 3.2.2样品检测 ................................................................................................... 6 3.3 判定标准 ............................................................................................................ 6
3.3.1 盐碘判定标准 .......................................................................................... 6 3.3.2碘缺乏病消除标准 ................................................................................... 6 3.3.3WHO/UNICEF/ICCIDD 标准 .................................................................. 6 3.4数据分析和处理方法 ......................................................................................... 6 4实验结果与讨论 ........................................................................................................... 7
4.1盐碘检测结果 ..................................................................................................... 7 4.2居民尿碘含量检测结果 ..................................................................................... 7
4.2.1碘标准曲线的绘制 ................................................................................... 7 4.2.2尿碘检测结果 ........................................................................................... 7 4.3不同食用盐碘浓度与尿碘中位数关系 ............................................................. 8 5小结 .............................................................................................................................. 11 参考文献 ........................................................................................................................ 12 致 谢 ................................................................................................. 错误!未定义书签。 附录Ⅰ英文翻译 ............................................................................................................ 14 附录Ⅱ英文原文 ............................................................................................................ 19
[摘要]目的 了解舟山市普陀区居民食用盐碘和尿碘的含量,为是否需要长期食用加碘盐提供科学依据。方法 2010 年4~6 月分别采集普陀市区及其所辖各县、镇部分居民家中正在使用的食盐进行盐碘测定,抽取相应家庭的尿样进行尿碘的测定。盐碘测定采用硫代硫酸钠滴定法,尿碘测定采用砷铈催化分光光度法。对盐碘值与尿碘值的相关性进行分析。结果 检测盐样586份,平均碘盐覆盖率为99.83%,居民合格碘盐食用率为97.95%;共检测1438份尿样,平均尿碘中位数为325μg/L,尿碘值< 50μg /L 所占比例为4.1%,尿碘值< 100μg/L 所占比例为18.7,尿碘值>300μg/L 所占比例为20.05%。结论 舟山市普陀区居民盐碘、尿碘含量达到碘缺乏病消除标准,但有20%左右的居民碘摄入过量,提示可能会引起各种甲状腺疾病。对盐碘和尿碘值进行拟合,得到回归方程为:y= 166 + 4.10x(r=0.9700),线性相关性好。 [关键词] 盐碘;尿碘;甲状腺疾病
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Putuo District of Zhoushan City,populationintake of salt iodine and urine iodine Correlation Analysis
[Abstract] Objective : To understand Residents of the Putuo District of Zhoushan City
edible salt iodine and urine iodine levels and may need long-term consumption of iodized salt to provide a scientific basis.
Method:In April~June of 2010 collected some residents’ home are being used the salt from Putuo and under the jurisdiction of the urban counties,town for salt iodine measurement, taken the corresponding family of urine samples for determined urinary iodine content. Determination of salt iodine titration using sodium thiosulfate, urinary iodine was determined by arsenic Ce catalytic spectrophotometry. Urinary iodine and salt iodine analysis of the correlation.
Results: 586 salt samples were tested, with an average 99.83% coverage of iodized salt, the residents was 97.95% of qualified iodized salt; 1438 copies were detected in urine, the average median urinary iodine 325μg / L, urinary iodine <50μg / L accounted for 4.1%, urinary iodine <100μg / L accounted for 18.7, urinary iodine> 300μg / L accounted for 20.05%. Putuo District, Zhoushan City residents Conclusion salt iodine and urine iodine content standards to eliminate iodine deficiency disorders, but 20% of the residents of excessive iodine intake, suggesting that may cause a variety of thyroid diseases. Salt iodine and urinary iodine were fitted, the regression equation: y = 166 + 4.10x (r = 0.9700), linear correlation is good.
[Key words] Salt iodine; Urinary iodine; Thyroid disease
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